OPTN Antikörper (AA 241-577)

Produktnummer ABIN3032098

Produktdetails anti-OPTN Antikörper

Target: OPTN (Optineurin (OPTN))

Bindungsspezifität: AA 241-577

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OPTN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 241-577) was used as the immunogen for this Optineurin antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Optineurin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Optineurin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu OPTN

Target: OPTN (Optineurin (OPTN))

Andere Bezeichnung: Optineurin (OPTN Produkte)

Synonyme: nrp antikoerper, fip2 antikoerper, hip7 antikoerper, hypl antikoerper, glc1e antikoerper, tfiiia-intp antikoerper, ALS12 antikoerper, FIP2 antikoerper, GLC1E antikoerper, HIP7 antikoerper, HYPL antikoerper, NRP antikoerper, TFIIIA-INTP antikoerper, Fip2 antikoerper, 4930441O07Rik antikoerper, fj52f04 antikoerper, si:ch211-240l19.3 antikoerper, wu:fj52f04 antikoerper, zgc:66386 antikoerper, zgc:77868 antikoerper, optineurin antikoerper, optineurin L homeolog antikoerper, OPTN antikoerper, optn antikoerper, Optn antikoerper, optn.L antikoerper

Hintergrund: OPTN is also known as NRP, FIP2 or HYPL. This gene encodes the coiled-coil containing protein Optineurin which may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize < a href=../search_result.php?search_txt=TNFa>tumor necrosis factor-alpha or < a href=../search_result.php?search_txt=fas ligand>Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. It may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the < a href=../search_result.php?search_txt=rab8>RAB8, < a href=../search_result.php?search_txt=huntingtin>Huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

Gen-ID: 10133

Pathways: M Phase