NRF1 Antikörper (Middle Region)
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- Target Alle NRF1 Antikörper anzeigen
- NRF1 (Nuclear Respiratory Factor 1 (NRF1))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NRF1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Aufreinigung
- Antigen affinity
- Immunogen
- An amino acid sequence from the middle region of human Nuclear Respiratory Factor 1 (QHGREDLLYAFEDQQTQ) was used as the immunogen for this NRF1 antibody (100% homologous in human, mouse and rat).
- Isotyp
- IgG
- Top Product
- Discover our top product NRF1 Primärantikörper
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- Applikationshinweise
- The stated application concentrations are suggested starting amounts. Titration of the NRF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Lagerung
- -20 °C
- Informationen zur Lagerung
- After reconstitution, the NRF1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Target
- NRF1 (Nuclear Respiratory Factor 1 (NRF1))
- Andere Bezeichnung
- NRF1 (NRF1 Produkte)
- Synonyme
- ALPHA-PAL antikoerper, C87038 antikoerper, D6Ertd415e antikoerper, SC:BZ3C13.1 antikoerper, SC:bZ3C13.2 antikoerper, ube2h antikoerper, Nfe2l1_retired antikoerper, IBR/F antikoerper, NRF1 antikoerper, alpha-pal antikoerper, nrf-1 antikoerper, LOC100220087 antikoerper, nuclear respiratory factor 1 antikoerper, nuclear respiratory factor 1 S homeolog antikoerper, NRF1 antikoerper, Nrf1 antikoerper, nrf1 antikoerper, nrf1.S antikoerper
- Hintergrund
- Nuclear Respiratory Factor 1 is also known as Alpha-Pal. Efiok et al.(1994) identified genes containing NRF1-binding sequences and found that these could be classified either as cellular proliferation genes, or as genes regulating the growth-responsive metabolic pathways of energy transduction, translation, and replication. Virbasius and Scarpulla(1994) noted that the nuclear-encoded mitochondrial transcription factor< a href=http://www.nsjbio.com/search_result.php?search_txt=tfam>TFAMcontains potential binding sites for NRF1, NRF2(GABPA) and SP1 within the promoter region. With use of binding and electrophoretic mobility shift assays, DNase footprinting, and mutation analysis of recombinant proteins, they demonstrated specific and functional binding of< a href=http://www.nsjbio.com/search_result.php?search_txt=nrf1>NRF1and< a href=http://www.nsjbio.com/search_result.php?search_txt=nrf2>NRF2to the TFAM promoter region.
- UniProt
- Q16656
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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