NK2 Homeobox 5 Antikörper (Middle Region)

Produktnummer ABIN3032007

Produktdetails anti-NK2 Homeobox 5 Antikörper

Target: NK2 Homeobox 5 (NKX2-5)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NK2 Homeobox 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the middle region of human Homeobox protein Nkx-2.5 (AKDPRAEKKELCALQKAVELEKTEADNAER) was used as the immunogen for this Nkx2-5 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Nkx2-5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Nkx2-5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu NK2 Homeobox 5

Target: NK2 Homeobox 5 (NKX2-5)

Andere Bezeichnung: Nkx2-5 (NKX2-5 Produkte)

Synonyme: CHNG5 antikoerper, CSX antikoerper, CSX1 antikoerper, HLHS2 antikoerper, NKX2.5 antikoerper, NKX2E antikoerper, NKX4-1 antikoerper, VSD3 antikoerper, Csx antikoerper, Nkx-2.5 antikoerper, Nkx2.5 antikoerper, tinman antikoerper, nk2.5 antikoerper, nkx2-5 antikoerper, zgc:111912 antikoerper, AR2 antikoerper, XNkx2-5 antikoerper, csx antikoerper, nkx-2.5 antikoerper, nkx2-5b antikoerper, nkx2.5 antikoerper, NKX2-5 antikoerper, Nkx2-5 antikoerper, csx1 antikoerper, nkx2e antikoerper, XNkx-2.5 antikoerper, CNKX-2.5 antikoerper, NKX-2.5 antikoerper, NK2 homeobox 5 antikoerper, NK2 homeobox 5 S homeolog antikoerper, NKX2-5 antikoerper, Nkx2-5 antikoerper, nkx2.5 antikoerper, nkx2-5.S antikoerper, nkx2-5 antikoerper

Hintergrund: Homeobox protein Nkx-2.5, also known as NKX2E or CSX, is a protein that in humans is encoded by the NKX2-5 gene. It is mapped to 5q35.1. Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. Nkx2-5 and Tbx5 directly bound to the promoter of the gene encoding cardiac-specific natriuretic peptide precursor type A (NPPA) in tandem, and both transcription factors showed synergistic activation. Nkx2-5 is essential in cardiac development, and mutations in the protein cause various congenital heart malformations.

Gen-ID: 1482

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development