MYD88 Antikörper (AA 44-264)

Produktnummer ABIN3031893

Produktdetails anti-MYD88 Antikörper

Target: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Bindungsspezifität: AA 44-264

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYD88 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 44-264) was used as the immunogen for this MyD88 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Titration of the MyD88 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: The MyD88 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze/thaws.

Details zu MYD88

Target: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Andere Bezeichnung: MyD88 (MYD88 Produkte)

Synonyme: MYD88D antikoerper, XMyD88 antikoerper, myd88d antikoerper, MGC84928 antikoerper, CG2078 antikoerper, DMMYD88 antikoerper, DmMyD88 antikoerper, DmMyd88 antikoerper, Dmel\\CG2078 antikoerper, EP(2)2535 antikoerper, Kra antikoerper, LD20892 antikoerper, MYD88 antikoerper, MyD88 antikoerper, Myd88F antikoerper, dMyD88 antikoerper, dMyd88 antikoerper, kra antikoerper, myd88 antikoerper, zgc:103541 antikoerper, GB12344 antikoerper, NV10640 antikoerper, myd88-a antikoerper, myd88-b antikoerper, myeloid differentiation primary response 88 antikoerper, myeloid differentiation primary response 88 S homeolog antikoerper, myeloid differentiation primary response gene 88 antikoerper, CG2078 gene product from transcript CG2078-RB antikoerper, myeloid differentiation primary response protein MyD88-A antikoerper, myeloid differentiation primary response protein MyD88 antikoerper, myeloid differentiation factor 88 antikoerper, myeloid differentiation primary response 88 L homeolog antikoerper, MYD88 antikoerper, myd88.S antikoerper, Myd88 antikoerper, myd88 antikoerper, LOC413194 antikoerper, LOC100118553 antikoerper, LOC575153 antikoerper, myd88.L antikoerper

Hintergrund: MyD88 is a cytosolic adapter protein that plays a central role in the< a href=../antibody_product_list.php?id=35>innateand adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and< a href=../tlr-toll-like-receptor-antibodies.html>Toll-like receptorsignaling pathways. Inhibiting the IL1R/MyD88 pathway in vivo could block the damage from acute inflammation that occurs in response to sterile cell death, and do so in a way that might not compromise tissue repair or host defense against pathogens.

Gen-ID: 4615

Pathways: NF-kappaB Signalweg, TLR Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades