MFN2 Antikörper (AA 601-757)
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- Target Alle MFN2 Antikörper anzeigen
- MFN2 (Mitofusin 2 (MFN2))
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Bindungsspezifität
- AA 601-757
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MFN2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Antigen affinity
- Immunogen
- Human partial recombinant protein (AA 601-757) was used as the immunogen for this MFN2 antibody.
- Isotyp
- IgG
- Top Product
- Discover our top product MFN2 Primärantikörper
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- Applikationshinweise
- The stated application concentrations are suggested starting amounts. Titration of the MFN2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Lagerung
- -20 °C
- Informationen zur Lagerung
- After reconstitution, the MFN2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Target
- MFN2 (Mitofusin 2 (MFN2))
- Andere Bezeichnung
- MFN2 (MFN2 Produkte)
- Synonyme
- CG3869 antikoerper, Dmel\\CG3869 antikoerper, MARF antikoerper, Marf-1 antikoerper, Mfn antikoerper, anon-WO0125274.3 antikoerper, dMFN antikoerper, dMfn antikoerper, dmfn antikoerper, marf antikoerper, mfn antikoerper, mfn2 antikoerper, MFN2 antikoerper, hsg antikoerper, cmt2a antikoerper, cprp1 antikoerper, cmt2a2 antikoerper, CMT2A antikoerper, CMT2A2 antikoerper, CPRP1 antikoerper, HSG antikoerper, D630023P19Rik antikoerper, Fzo antikoerper, mg:cb01g09 antikoerper, si:dkeyp-104h9.2 antikoerper, wu:fb79a11 antikoerper, mitofusin 2 antikoerper, Mitochondrial assembly regulatory factor antikoerper, mitofusin-2 antikoerper, mitofusin 2 L homeolog antikoerper, MFN2 antikoerper, Marf antikoerper, mfn2 antikoerper, LOC100186475 antikoerper, Mfn2 antikoerper, mfn2.L antikoerper
- Hintergrund
- Mitofusin-2 is a protein that in humans is encoded by the MFN2 gene. It is mapped to chromosome 1 and encodes a 757-amino acid protein that contains an ATP/GTP-binding site motif. This gene is expressed in many tissues and cell lines such as brain and KG-1 with the highest expression in heart and skeletal muscle. It has been found that MFN2 triggers mitochondrial energization, at least in part, by regulating OXPHOS expression through signals that are independent of its role as a mitochondrial fusion protein. And it contributes to the maintenance and operation of the mitochondrial network. Axonal CMT type 2A and autosomal dominant HMSN VI are caused by MFN2 and mutations of, which emphasizes its important role of mitochondrial function for both optic atrophies and peripheral neuropathies.
- Gen-ID
- 9927
- Pathways
- Skeletal Muscle Fiber Development
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