MFN1 Antikörper (N-Term)

Produktnummer ABIN3031817

Produktdetails anti-MFN1 Antikörper

Target: MFN1 (Mitofusin 1 (MFN1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MFN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the N-terminal of human Mitofusin 1 (DQLLEFVTEGSHFVEATYKNPELDRIA) was used as the immunogen for this MFN1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the MFN1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the MFN1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu MFN1

Target: MFN1 (Mitofusin 1 (MFN1))

Andere Bezeichnung: MFN1 (MFN1 Produkte)

Synonyme: mfn1 antikoerper, zgc:66150 antikoerper, mitofusin-1 antikoerper, MFN1 antikoerper, MFN2 antikoerper, hfzo1 antikoerper, hfzo2 antikoerper, 2310002F04Rik antikoerper, 6330416C07Rik antikoerper, D3Ertd265e antikoerper, HR2 antikoerper, mKIAA4032 antikoerper, Fzo1b antikoerper, mitofusin 1b antikoerper, mitofusin 1 antikoerper, mitofusin 1 S homeolog antikoerper, mfn1b antikoerper, MFN1 antikoerper, mfn1.S antikoerper, mfn1 antikoerper, Mfn1 antikoerper

Hintergrund: Mitofusin-1 is a protein that in humans is encoded by the MFN1 gene. It is a mitochondrial member of the dynamin family of molecules. It is ubiquitously expressed, and found in the outer mitochondrial membrane. The protein encoded by this gene is a mediator of mitochondrial fusion, and thereby contribute to the dynamic balance between fusion and fission that determines mitochondria morphology. MFN1 is known to form oligomers, either with itself or MFN-2, and to undergo ubiquitination by MARCH5. It has two key domains, One is a coiled-coil region that mediates MFN-1/2 binding, and a second is a GTPase domain whose cleavage of GTP is necessary for membrane fusion. Overexpression causes perinuclear mitochondrial clustering.

Gen-ID: 55669