LTK
Reaktivität: Human
ELISA
Wirt: Kaninchen
Polyclonal
HRP
Applikationshinweise
The stated application concentrations are suggested starting amounts. Titration of the LTK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
-20 °C
Informationen zur Lagerung
After reconstitution, the LTK antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Leukocyte tyrosine kinase, also known as TYK1, is an enzyme that in humans is encoded by the LTK gene. The protein encoded by this gene is a member of the ALK/LTK receptor family of receptor tyrosine kinases (RTKs) whose ligand is unknown. Toyoshima et al.(1993) cloned a set of cDNAs representing differently spliced human LTK mRNAs. Liao et al.(1996) found that the mouse Ltk gene is closely linked to the Tyro3 gene which maps to mouse chromosome 2. Thus, the gene produces not only the putative receptor tyrosine kinase for an unknown ligand but also multiple protein products that may have different functions.