KLF5 Antikörper (Middle Region)

Produktnummer ABIN3031574

Produktdetails anti-KLF5 Antikörper

Target: KLF5 (Kruppel-Like Factor 5 (Intestinal) (KLF5))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLF5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the middle region of human Kruppel-like factor 5 (HKKYRRDSASVVDQFFTD) was used as the immunogen for this KLF5 antibody (100% homologous in human, mouse and rat).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the KLF5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the KLF5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu KLF5

Target: KLF5 (Kruppel-Like Factor 5 (Intestinal) (KLF5))

Andere Bezeichnung: KLF5 (KLF5 Produkte)

Synonyme: KLF5 antikoerper, klf5 antikoerper, MGC115081 antikoerper, BTEB2 antikoerper, Bteb2 antikoerper, IKLF antikoerper, bteb2 antikoerper, 4930520J07Rik antikoerper, CKLF antikoerper, Kruppel like factor 5 antikoerper, Kruppel-like factor 5 (intestinal) S homeolog antikoerper, Kruppel-like factor 5 antikoerper, KLF5 antikoerper, klf5.S antikoerper, Klf5 antikoerper

Hintergrund: Kruppel-like factor 5 is a protein that in humans is encoded by the KLF5 gene. It is also known as BTEB2. This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Suske et al.(2005) stated that the human gene maps to chromosome 13q21.33, and the mouse gene to chromosome 14E2.1. Sogawa et al.(1993) isolated a cDNA encoding KLF5. The predicted protein contains 3 consecutive zinc finger motifs near the C terminus. The zinc finger domains were 59 % and 64 % identical to those of Sp1 (189906) and BTEB1, respectively. Both KLF5 and Sp1 have a short basic region preceding the zinc finger motifs that may play an auxiliary role in DNA binding. The N-terminal region of KLF5 is proline rich. Recombinant KLF5 protein and Sp1 showed very similar DNA-binding specificity in vitro. When expressed in mammalian cells, KLF5 activated the transcription of a reporter gene fused to a GC box-containing promoter. Sogawa et al.(1993) also identified the rat homolog.

UniProt: Q13887