KLK9
Reaktivität: Maus
IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
Alexa Fluor 680
Applikationshinweise
The stated application concentrations are suggested starting amounts. Titration of the Kallikrein 9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
-20 °C
Informationen zur Lagerung
After reconstitution, the Kallikrein 9 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Kallikrein-related peptidase 9, also known as KLK9 or KLK-L3, belongs to the kallikrein subgroup of serine proteases, which have diverse physiologic functions in many tissues. The KLK9 gene contains 5 coding exons and is mapped to 19q13.41. The gene is regulated by steroid hormones in a human breast cancer cell line. Yousef et al.(2001) performed a quantitative analysis of KLK9 expression in ovarian cancer. The results indicated that KLK9 is under steroid hormone regulation in ovarian and breast cancer cell lines. KLK9 is a potential independent favorable prognostic marker for early-stage, low-grade, optimally debulked ovarian cancer patients.