IGFBP3 Antikörper (Middle Region)

Produktnummer ABIN3031353

Produktdetails anti-IGFBP3 Antikörper

Target: IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGFBP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the middle region of human IGFBP3 (IKKGHAKDSQRYKVDYE) was used as the immunogen for this IGFBP3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the IGFBP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the IGFBP3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu IGFBP3

Target: IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))

Andere Bezeichnung: IGFBP3 (IGFBP3 Produkte)

Synonyme: BP-53 antikoerper, IBP3 antikoerper, AI649005 antikoerper, IGFBP-3 antikoerper, IGgfbp3 antikoerper, IGF-BP3 antikoerper, zgc:91788 antikoerper, IGFBP3 antikoerper, igfbp3 antikoerper, insulin like growth factor binding protein 3 antikoerper, insulin-like growth factor binding protein 3 antikoerper, IGFBP3 antikoerper, Igfbp3 antikoerper, igfbp3 antikoerper, IGFBP-3 antikoerper, LOC100305016 antikoerper

Hintergrund: Insulin-like growth fator-binding protein 3, is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. IGFBP3 is located on chromosome 7. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit(IGFALS) and either insulin-like growth factor(IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UniProt: P17936

Pathways: Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagie, Smooth Muscle Cell Migration, Growth Factor Binding