Inhibitor of Growth Family, Member 3 (ING3) (AA 294-304) Antikörper

Details zu Produkt Nr. ABIN303108, Anbieter: Anmelden zum Anzeigen
Antigen
  • ING3
  • Eaf4
  • ING2
  • MEAF4
  • p47ING3
  • 1300013A07Rik
  • P47ING3
  • zgc:56327
  • inhibitor of growth family member 3
  • inhibitor of growth family, member 3
  • inhibitor of growth protein 3
  • inhibitor of growth family member 3 L homeolog
  • ING3
  • Ing3
  • CpipJ_CPIJ009396
  • ing3
  • ing3.L
Epitop
AA 294-304
7
7
5
4
4
2
2
2
2
1
1
1
1
Reaktivität
Huhn, Human, Maus
53
28
24
5
4
4
4
4
4
3
3
2
2
1
1
Wirt
Ziege
34
11
8
Klonalität
Polyklonal
Konjugat
Unkonjugiert
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
46
34
19
13
6
6
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Synthetic peptide corresponding to aa 294-304 of Human ING3 protein (Inhibitor of growth family, member 3).
Spezifität Recognizes ING3 (294-304).
Reinigung Immunoaffinity Chromatography.
Antigen Inhibitor of Growth Family, Member 3 (ING3)
Andere Bezeichnung ING3 (ING3 Antibody Abstract)
Hintergrund P47 ING3 is a tumor suppressor protein similar to ING1 that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Over-expression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Multiple alternatively spliced transcript variants have been observed. The accession number listed below is for variant that encodes the longest isoform.Synonyms: HSPC301, Inhibitor of growth protein 3, p47ING3
Gen-ID 54556
NCBI Accession NP_061944
UniProt Q9NXR8
Applikations-hinweise Immunohistochemistry on Paraffin Sections (2.5 μg/mL). Western Blot (1/200-1/2000). Immunofluorescence. ELISA (1/10000-1/40000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1.0 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Bilder des Herstellers
 image for anti-Inhibitor of Growth Family, Member 3 (ING3) (AA 294-304) antibody (ABIN303108) anti-Inhibitor of Growth Family, Member 3 (ING3) (AA 294-304) antibody
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