FOXM1 Antikörper (AA 411-763)

Produktnummer ABIN3030988

Produktdetails anti-FOXM1 Antikörper

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Bindungsspezifität: AA 411-763

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 411-763) was used as the immunogen for this FOXM1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the FOXM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the FOXM1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu FOXM1

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Andere Bezeichnung: FOXM1 (FOXM1 Produkte)

Synonyme: FKHL16 antikoerper, FOXM1B antikoerper, HFH-11 antikoerper, HFH11 antikoerper, HNF-3 antikoerper, INS-1 antikoerper, MPHOSPH2 antikoerper, MPP-2 antikoerper, MPP2 antikoerper, PIG29 antikoerper, TGT3 antikoerper, TRIDENT antikoerper, FOXM1 antikoerper, AA408308 antikoerper, AW554517 antikoerper, BB238854 antikoerper, Fkh16 antikoerper, Foxm1b antikoerper, HFH-11B antikoerper, Mpm2 antikoerper, WIN antikoerper, Trident antikoerper, fkhl16 antikoerper, foxm1l antikoerper, hfh-11 antikoerper, mpp2 antikoerper, zgc:63854 antikoerper, forkhead box M1 antikoerper, forkhead box M1 S homeolog antikoerper, FOXM1 antikoerper, Foxm1 antikoerper, foxm1 antikoerper, foxm1.S antikoerper

Hintergrund: Forkhead box protein M1 is encoded by the FOXM1 gene. It is a member of the FOX family of transcription factors. FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases and also in the control of cell proliferation. The gene is now known as a human proto-oncogene. Abnormal upregulation of the protein is involved in the oncogenesis of basal cell carcinoma, the most common human cancer worldwide. It is hypothesized that FOXM1 induces cancer initiation through stem/progenitor cell expansion. Additionally, FOXM1 has been shown to modulate the epigenome. It was found that overexpression of the protein brain washes normal cells to adopt cancer-like epigenome.

Gen-ID: 2305

Pathways: Positive Regulation of Response to DNA Damage Stimulus