Cullin 3 Antikörper (Middle Region)

Produktnummer ABIN3030578

Produktdetails anti-Cullin 3 Antikörper

Target: Cullin 3 (CUL3)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cullin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the middle region of human Cullin-3 (DVFERYYKQHLARRLLTNK) was used as the immunogen for this CUL3 antibody (100% homologous in human, mouse and rat).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the CUL3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the CUL3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Cullin 3

Target: Cullin 3 (CUL3)

Andere Bezeichnung: CUL3 (Cullin-3) (CUL3 Produkte)

Synonyme: CUL-3 antikoerper, Cullin-3 antikoerper, CUL-3-A antikoerper, Cullin-3-A antikoerper, cul3 antikoerper, cul3a antikoerper, CUL-3-B antikoerper, Cullin-3-B antikoerper, cul3b antikoerper, wu:fc37e01 antikoerper, CUL3 antikoerper, ATCUL3 antikoerper, ATCUL3A antikoerper, CUL3A antikoerper, T24P13.25 antikoerper, cullin 3 antikoerper, cullin 3A antikoerper, PHA2E antikoerper, AI467304 antikoerper, AW146203 antikoerper, mKIAA0617 antikoerper, cullin 3 antikoerper, cullin 3 L homeolog antikoerper, cullin 3 S homeolog antikoerper, cullin-3 antikoerper, Cullin-3 (CUL-3) antikoerper, cullin 3a antikoerper, CULlin antikoerper, CUL3 antikoerper, cul3 antikoerper, cul3.L antikoerper, cul3.S antikoerper, PTRG_11586 antikoerper, Smp_117580 antikoerper, cul3a antikoerper, Cul3 antikoerper, cul-3 antikoerper

Hintergrund: Cullin-3 is a protein that in humans is encoded by the CUL3 gene. Kipreos et al.(1996) identified a conserved gene family, designated cullins, with at least 5 members in nematodes, 6 in humans, and 3 in S. cerevisiae. Hartz (2012) mapped the gene to chromosome 2q36.2 based on an alignment of the CUL3 sequence with the genomic sequence (GRCh37). Sumara et al.(2007) found that KLHL9, KLHL13, and CUL-3 interacted directly in a 370-kD protein complex in HeLa cell lysates. Rondou et al.(2008) showed that interaction between KLHL12 and the CUL3 ubiquitin ligase complex directed ubiquitination of dopamine receptor D4(DRD4). KLHL12 interacted directly with CUL-3 and with the polymorphic intracellular loop-3 of D4. By immunoprecipitation analysis of HeLa cells and HCT116 human colon carcinoma cells expressing epitope-tagged proteins, Kigoshi et al.(2011) showed that KLHL7 interacted with CUL-3 and ROC1(RBX1).

UniProt: Q13618

Pathways: M Phase