Arrestin 3 Antikörper (C-Term)
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- Target Alle Arrestin 3 (ARRB2) Antikörper anzeigen
- Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Arrestin 3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- Antigen affinity
- Immunogen
- An amino acid sequence from the C-terminus of human ARRB2 (RLKGMKDDDYDDQLC) was used as the immunogen for this Beta Arrestin 2 antibody.
- Isotyp
- IgG
- Top Product
- Discover our top product ARRB2 Primärantikörper
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- Applikationshinweise
- The stated application concentrations are suggested starting amounts. Titration of the Beta Arrestin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Lagerung
- -20 °C
- Informationen zur Lagerung
- After reconstitution, the Beta Arrestin 2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Target
- Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
- Andere Bezeichnung
- beta Arrestin 2 (ARRB2 Produkte)
- Synonyme
- ARRB2 antikoerper, arb2 antikoerper, arr2 antikoerper, arrestin antikoerper, barr2 antikoerper, betaarr2 antikoerper, ARB2 antikoerper, ARR2 antikoerper, BARR2 antikoerper, BARRES antikoerper, AI326910 antikoerper, AW122872 antikoerper, arrb2 antikoerper, zgc:64007 antikoerper, arrestin beta 2 antikoerper, arrestin, beta 2 antikoerper, arrestin beta 2 L homeolog antikoerper, arrestin, beta 2b antikoerper, ARRB2 antikoerper, arrb2 antikoerper, Arrb2 antikoerper, arrb2.L antikoerper, arrb2b antikoerper
- Hintergrund
- Beta Arrestin 2 is an intracellular protein that in humans is encoded by the ARRB2 gene. Members of the arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals, as well as having signalling roles in their own right. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptorfunction in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Beta-arrestins were originally discovered in the context of heterotrimeric G protein-coupled receptor desensitization, but they also function in internalization and signaling of these receptors.
- UniProt
- P32121
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling
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