Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) Antikörper

Details zu Produkt Nr. ABIN3029897
Antigen
Reaktivität
Human
162
45
44
2
2
1
1
1
1
1
1
Wirt
Maus
115
45
7
Klonalität (Klon)
Monoklonal ()
Konjugat
Unkonjugiert
12
7
7
7
7
7
2
2
2
2
2
2
Applikation
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
149
89
86
35
29
27
14
7
6
4
1
Optionen
Immunogen This ALDH2 antibody was produced from a mouse immunized with ALDH2 recombinant protein.
Klon 138CT22-3-8
Isotyp IgG1, kappa
Reinigung Purified
Antigen
Andere Bezeichnung ALDH2 (ALDH2 Antibody Abstract)
Hintergrund This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix.
UniProt P05091
Applikations-hinweise Titration of the ALDH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer In 1X PBS pH 7.4 with 0.09 % sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Aliquot the ALDH2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Bilder des Herstellers
Image no. 1 for anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) antibody (ABIN3029897) ALDH2 antibody flow cytometric analysis of HepG2 cells (red) compared to a negative c...
Image no. 2 for anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) antibody (ABIN3029897) Western blot analysis of lysate from NCI-H292, A549, HepG2 cell line (left to right) ...
Image no. 3 for anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) antibody (ABIN3029897) ALDH2 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded ...
Image no. 4 for anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) antibody (ABIN3029897) Confocal immunofluorescent analysis of ALDH2 antibody with HepG2 cells followed by Al...
Image no. 5 for anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) antibody (ABIN3029897) Western blot analysis of lysate from NCI-H292, A549, HepG2 cell line (left to right) ...
Image no. 6 for anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) antibody (ABIN3029897) Confocal immunofluorescent analysis of ALDH2 antibody with HepG2 cells followed by Al...
Image no. 7 for anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) antibody (ABIN3029897) ALDH2 antibody flow cytometric analysis of HepG2 cells (red) compared to a negative c...