ABI1 Antikörper (C-Term)

Produktnummer ABIN3029824

Produktdetails anti-ABI1 Antikörper

Target: ABI1 (Abl-Interactor 1 (ABI1))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human SSH3BP1 (WYEGVCNRVTGL) was used as the immunogen for this SSH3BP1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the SSH3BP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the SSH3BP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu ABI1

Target: ABI1 (Abl-Interactor 1 (ABI1))

Andere Bezeichnung: SSH3BP1 (ABI1 Produkte)

Synonyme: ABI-1 antikoerper, ABLBP4 antikoerper, E3B1 antikoerper, NAP1BP antikoerper, SSH3BP antikoerper, SSH3BP1 antikoerper, NAP1 antikoerper, Ssh3bp1 antikoerper, E3b1 antikoerper, abi1 antikoerper, wu:fc66g09 antikoerper, wu:fk56a10 antikoerper, zgc:73174 antikoerper, MGC84356 antikoerper, ABI1 antikoerper, abi-1 antikoerper, e3b1 antikoerper, nap1bp antikoerper, ssh3bp antikoerper, ssh3bp1 antikoerper, wu:fe48a10 antikoerper, zgc:153534 antikoerper, DKFZp469P1319 antikoerper, abl interactor 1 antikoerper, abl-interactor 1 antikoerper, abl-interactor 1a antikoerper, abl interactor 1 S homeolog antikoerper, abl-interactor 1b antikoerper, Abl-interactor 1 antikoerper, Abl interactor 1 antikoerper, ABI1 antikoerper, Abi1 antikoerper, abi1a antikoerper, abi1.S antikoerper, abi1 antikoerper, abi1b antikoerper, Bm1_44660 antikoerper, LOAG_04356 antikoerper

Hintergrund: ABI1 is a human homolog of mouse Abl-interactor-1(Abi1), mapped on 10p11.2. ABI1 participates in the transduction of signals from Ras to Rac by regulating Rac-specific guanine nucleotide exchange factor(GEF) activities. ABI1 dramatically promoted ABL1-mediated tyrosine phosphorylation of MENA, but not of other substrates. Abi-1 regulates c-Abl-mediated phosphorylation of Mena by interacting with both proteins. ABI1 plays a role in the leukemogenesis by translocating to MLL.

UniProt: Q8IZP0

Pathways: RTK Signalweg, Response to Water Deprivation, ER-Nucleus Signaling