TFF1 Antikörper (AA 67-84)

Produktnummer ABIN3029755

Produktdetails anti-TFF1 Antikörper

Target: TFF1 (Trefoil Factor 1 (TFF1))

Bindungsspezifität: AA 67-84

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Amino acids 67-84 (WCFYPNTIDVPPEEECEF-human) were used as the immunogen for this pS2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Titration of the pS2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: The lyophilized pS2 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu TFF1

Target: TFF1 (Trefoil Factor 1 (TFF1))

Andere Bezeichnung: pS2 (Estrogen Inducible Protein) (TFF1 Produkte)

Synonyme: BCEI antikoerper, D21S21 antikoerper, HP1.A antikoerper, HPS2 antikoerper, pNR-2 antikoerper, pS2 antikoerper, Bcei antikoerper, PS2 antikoerper, bcei antikoerper, d21s21 antikoerper, hp1.a antikoerper, hps2 antikoerper, p1 antikoerper, p1-a antikoerper, pnr-2 antikoerper, ps2 antikoerper, tff1 antikoerper, xP1 antikoerper, xp1-L antikoerper, xp1 antikoerper, TFF1 antikoerper, Ps2 antikoerper, trefoil factor 1 antikoerper, trefoil factor 1 S homeolog antikoerper, trefoil factor 1, gene 2 S homeolog antikoerper, TFF1 antikoerper, Tff1 antikoerper, tff1.S antikoerper, tff1.2.S antikoerper, LOC100358238 antikoerper

Hintergrund: Trefoil factor 1, also known as TFF1 and Estrogen inducible factor pS2, is a protein that in humans is encoded by the TFF1 gene. Family members are stable secretory proteins expressed in gastrointestinal mucosa that protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. The protein in normal human urine inhibited the growth of calcium oxalate crystals, and lack of pS2 may contribute to the development of idiopathic calcium oxalate kidney stones. Urinary pS2 showed an inhibitory potency similar to that of nephrocalcin, and inhibition was dose dependent and inhibited by pS2 antisera, particularly by antisera directed to the pS2 C terminus.

UniProt: P04155

Pathways: EGFR Signaling Pathway