C5 Antikörper (AA 1-77)

Produktnummer ABIN3029691

Produktdetails anti-C5 Antikörper

Target: C5 (Complement Component 5 (C5))

Bindungsspezifität: AA 1-77

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Rat partial recombinant protein (AA 1-77, alpha subunit) was used as the immunogen for this C5 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Titration of the C5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: The C5 antibody can be stored at 4°C to -20°C. After reconsititution, aliquot and store at -20°C. Avoid repeated freeze/thaws.

Details zu C5

Target: C5 (Complement Component 5 (C5))

Andere Bezeichnung: C5 (C5 Produkte)

Synonyme: C5 antikoerper, LOC565774 antikoerper, C5a antikoerper, C5b antikoerper, CPAMD4 antikoerper, Hc antikoerper, RGD1561905 antikoerper, He antikoerper, complement C5 antikoerper, complement component 5 antikoerper, hemolytic complement antikoerper, C5 antikoerper, c5 antikoerper, Hc antikoerper

Hintergrund: C5a is a protein fragment released from complement component C5. The protein plays an important role in inflammatory and cell killing processes. C5 is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. C5a plays a key role in increasing migration and adherence of neutrophils and monocytes to vessel walls. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to susceptibility to liver fibrosis and to rheumatoid arthritis.

Gen-ID: 362119

Pathways: Komplementsystem, Carbohydrate Homeostasis