Integrin beta 4 Antikörper (AA 28-266)

Produktnummer ABIN3028741

Produktdetails anti-Integrin beta 4 Antikörper

Target: Integrin beta 4 (ITGB4)

Bindungsspezifität: AA 28-266

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Integrin beta 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 28-266) was used as the immunogen for this ITGB4 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Titration of the ITGB4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the ITGB4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Integrin beta 4

Target: Integrin beta 4 (ITGB4)

Andere Bezeichnung: ITGB4 (ITGB4 Produkte)

Synonyme: AA407042 antikoerper, C230078O20 antikoerper, CD104 antikoerper, integrin subunit beta 4 antikoerper, integrin beta 4 antikoerper, ITGB4 antikoerper, Itgb4 antikoerper

Hintergrund: ITGB4, also known as CD104, is a receptor for the laminin proteins. It tends to associate with alpha 6 subunits and is likely to play a pivotal role in the biology of invasive carcinoma. It was found that ITGB4 was upregulated 6-fold by ZKSCAN3 in transfected human colon cancer cells compared with parental cells and ZKSCAN3 has been confirmed as the promoter of ITGB4 in vitro and in vivo. ITGB4 knockdown by short hairpin RNA countered ZKSCAN3-augmented anchorage-independent colony formation in the colon cancer cell lines.

UniProt: P16144

Pathways: Integrin Complex