MAPKAP1 Antikörper (C-Term)

Produktnummer ABIN3025251

Produktdetails anti-MAPKAP1 Antikörper

Target: MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPKAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein A purified antibody

Immunogen: A recombinant protein fragment from the C-terminal region of human SIN1 was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Provided assay concentrations are suggestions only, SIN1 antibody titration may be required for optimal results.\. Western blot: 1-3 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store frozen at -20°C or colder to avoid repeated freeze-thaw cycles.

Details zu MAPKAP1

Target: MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))

Andere Bezeichnung: SIN1 (MAPKAP1 Produkte)

Synonyme: CG10105 antikoerper, Dmel\\CG10105 antikoerper, dSin1 antikoerper, sin1 antikoerper, MAPKAP1 antikoerper, im:7143088 antikoerper, si:ch73-242f23.1 antikoerper, mip1 antikoerper, sin1b antikoerper, sin1g antikoerper, MGC53034 antikoerper, JC310 antikoerper, MIP1 antikoerper, SIN1 antikoerper, SIN1b antikoerper, SIN1g antikoerper, AI591529 antikoerper, D230039K05Rik antikoerper, Sin1 antikoerper, SAPK-interacting protein 1 antikoerper, mitogen-activated protein kinase associated protein 1 antikoerper, mitogen-activated protein kinase associated protein 1 L homeolog antikoerper, Sin1 antikoerper, MAPKAP1 antikoerper, mapkap1 antikoerper, Mapkap1 antikoerper, mapkap1.L antikoerper

Hintergrund: MTOR, or Mammalian target of rapamycin, a large protein kinase, is a regulator of cell growth and survival via its mTORC1 (mTOR + GBL + Raptor) and mTORC2 (mTOR + GBL + SIN1 + Rictor) complexes. SIN1 is an essential component of mTORC2, which activates Akt by phosphorylating Ser473. Phosphorylation of SIN1 at Thr86/398 causes its dissociation from the mTORC2 complex, inhibiting mTORC2s kinase activity.

Gen-ID: 79109

Pathways: PI3K-Akt Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events