UNC93B1 Antikörper (C-Term)

Produktnummer ABIN3024029

Produktdetails anti-UNC93B1 Antikörper

Target: UNC93B1 (Unc-93 Homolog B1 (UNC93B1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UNC93B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein A Affinity Chromatography

Immunogen: A recombinant protein fragment from the C-terminal portion of UNC93B was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.\. Western blot: 3-6 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the antibody and store frozen at -20°C or colder to avoid repeated freeze-thaw cycles.

Details zu UNC93B1

Target: UNC93B1 (Unc-93 Homolog B1 (UNC93B1))

Andere Bezeichnung: UNC93B (UNC93B1 Produkte)

Synonyme: UNC93 antikoerper, IIAE1 antikoerper, UNC93B antikoerper, Unc-93B1 antikoerper, Unc93b antikoerper, unc-93 homolog B1, TLR signaling regulator antikoerper, unc-93 homolog B1 (C. elegans) antikoerper, UNC93B1 antikoerper, Unc93b1 antikoerper

Hintergrund: UNC93B is part of the innate immune response via its direct interaction with the intracellular toll-like receptors TLR3, 7, and 9. UNC93B aids in the trafficing of these TLRs from the ER to the endolysosomes, where they bind ligands and initiate immune response. In the absence of UNC93B, these TLRs are unable to respond to foreign stimuli.

Gen-ID: 81622

Pathways: TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades