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LCP2 Antikörper (AA 284-533)

LCP2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3023382
  • Target Alle LCP2 Antikörper anzeigen
    LCP2 (Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2))
    Bindungsspezifität
    • 20
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 284-533
    Reaktivität
    • 61
    • 31
    • 14
    • 3
    Human
    Wirt
    • 46
    • 16
    • 1
    Kaninchen
    Klonalität
    • 42
    • 21
    Polyklonal
    Konjugat
    • 39
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser LCP2 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 12
    • 11
    • 8
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    KPPLPPTTER HERSSPLPGK KPPVPKHGWG PDRRENDEDD VHQRPLPQPA LLPMSSNTFP SRSTKPSPMN PLPSSHMPGA FSESNSSFPQ SASLPPYFSQ GPSNRPPIRA EGRNFPLPLP NKPRPPSPAE EENSLNEEWY VSYITRPEAE AALRKINQDG TFLVRDSSKK TTTNPYVLMV LYKDKVYNIQ IRYQKESQVY LLGTGLRGKE DFLSVSDIID YFRKMPLLLI DGKNRGSRYQ CTLTHAAGYP
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 284-533 of human LCP2 (NP_005556.1).
    Isotyp
    IgG
    Top Product
    Discover our top product LCP2 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    LCP2 (Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2))
    Andere Bezeichnung
    LCP2 (LCP2 Produkte)
    Synonyme
    AI323664 antikoerper, BB161688 antikoerper, SLP-76 antikoerper, SLP76 antikoerper, twm antikoerper, Slp76 antikoerper, lymphocyte cytosolic protein 2 antikoerper, Lcp2 antikoerper, LCP2 antikoerper
    Hintergrund
    SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72 % identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function.,LCP2,SLP-76,SLP76,Signal Transduction,Immunology & Inflammation,T Cell Receptor Signaling Pathway,LCP2
    Molekulargewicht
    60 kDa
    Gen-ID
    3937
    UniProt
    Q13094
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung
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