Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) Antikörper

Details zu Produkt Nr. ABIN3023022
Antigen
  • NR1H3
  • LXR-a
  • LXRA
  • RLD-1
  • AU018371
  • LXR
  • RLD1
  • Unr1
  • LXRalpha
  • LXR-alpha
  • im:7141239
  • wu:fd59b01
  • zgc:113339
  • zgc:158542
  • nuclear receptor subfamily 1 group H member 3
  • nuclear receptor subfamily 1, group H, member 3
  • NR1H3
  • nr1h3
  • Nr1h3
Reaktivität
Maus, Ratte (Rattus), Human
135
71
66
11
9
9
7
6
6
5
4
4
3
2
2
2
2
2
2
Wirt
Kaninchen
123
16
6
Klonalität
Polyklonal
Konjugat
Unkonjugiert
7
5
5
2
2
2
2
2
2
2
2
2
2
2
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
121
58
26
15
9
8
8
6
4
3
2
2
2
1
Optionen
Immunogen Recombinant protein of human NR1H3
Isotyp IgG
Reinigung Affinity purification
Antigen
Andere Bezeichnung NR1H3 (NR1H3 Antibody Abstract)
Hintergrund The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Synonyms: LXR-a, LXRA, RLD-1
Gen-ID 10062
UniProt Q13133
Pathways Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
Applikations-hinweise Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid freeze / thaw cycles
Lagerung -20 °C/-80 °C
Bilder des Herstellers
Western Blotting (WB) image for anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) antibody (ABIN3023022) Western blot analysis of extracts of HT29 cell lines, using NR1H3 antibody.
Western Blotting (WB) image for anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) antibody (ABIN3023022) Western blot analysis of extracts of various cell lines, using NR1H3 antibody.
Produkt verwendet in: Qian, Ma, Wu, Yu, Lin, Ying, Wen, Gao: "G004, a synthetic sulfonylurea compound, exerts anti-atherosclerosis effects by targeting SIRT1 in ApoE-/- mice." in: Vascular pharmacology, Vol. 89, pp. 49-57, 2017 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB)

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