XRCC3 Antikörper (AA 62-346)

Produktnummer ABIN3023006

Produktdetails anti-XRCC3 Antikörper

Target: XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))

Bindungsspezifität: AA 62-346

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XRCC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ILTALQLHQQ KERFPTQHQR LSLGCPVLDA LLRGGLPLDG ITELAGRSSA GKTQLALQLC LAVQFPRQHG GLEAGAVYIC TEDAFPHKRL QQLMAQQPRL RTDVPGELLQ KLRFGSQIFI EHVADVDTLL ECVNKKVPVL LSRGMARLVV IDSVAAPFRC EFDSQASAPR ARHLQSLGAT LRELSSAFQS PVLCINQVTE AMEEQGAAHG PLGFWDERVS PALGITWANQ LLVRLLADRL REEEAALGCP ARTLRVLSAP HLPPSSCSYT ISAEGVRGTP GTQSH

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 62-346 of human XRCC3 (NP_001093588.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-XRCC3 Antikörper (ABIN3023006)

Zhang, Tang, Jiang, Mao: "The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression." in: Oncogene, Vol. 36, Issue 36, pp. 5168-5176, (2017) (PubMed).

Dong, Wang, Wang, Zhang, Zhu, Gao, Yang, Qin, Liang, Chen, Deng, Ning, Liang, Gao, Xu: "A stress-induced cellular aging model with postnatal neural stem cells." in: Cell death & disease, Vol. 5, pp. e1116, (2014) (PubMed).

Details zu XRCC3

Target: XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))

Andere Bezeichnung: XRCC3 (XRCC3 Produkte)

Synonyme: CMM6 antikoerper, 4432412E01Rik antikoerper, AI182522 antikoerper, AW537713 antikoerper, MGC69118 antikoerper, im:7142103 antikoerper, zgc:101608 antikoerper, si:dkey-11b8.1 antikoerper, xrcc3 antikoerper, XRCC3 antikoerper, X-ray repair cross complementing 3 antikoerper, X-ray repair complementing defective repair in Chinese hamster cells 3 antikoerper, X-ray repair complementing defective repair in Chinese hamster cells 3 L homeolog antikoerper, XRCC3 antikoerper, Xrcc3 antikoerper, xrcc3.L antikoerper, xrcc3 antikoerper

Hintergrund: This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.,XRCC3,CMM6,Epigenetics & Nuclear Signaling,DNA Damage & Repair,XRCC3

Molekulargewicht: 37 kDa

Gen-ID: 7517

UniProt: O43542

Pathways: DNA Reparatur