PDE1B Antikörper (AA 190-536)

Produktnummer ABIN3022918

Produktdetails anti-PDE1B Antikörper

Target: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Bindungsspezifität: AA 190-536

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: RHNLISRFKI PTVFLMSFLD ALETGYGKYK NPYHNQIHAA DVTQTVHCFL LRTGMVHCLS EIELLAIIFA AAIHDYEHTG TTNSFHIQTK SECAIVYNDR SVLENHHISS VFRLMQDDEM NIFINLTKDE FVELRALVIE MVLATDMSCH FQQVKTMKTA LQQLERIDKP KALSLLLHAA DISHPTKQWL VHSRWTKALM EEFFRQGDKE AELGLPFSPL CDRTSTLVAQ SQIGFIDFIV EPTFSVLTDV AEKSVQPLAD EDSKSKNQPS FQWRQPSLDV EVGDPNPDVV SFRSTWVKRI QENKQKWKER AASGITNQMS IDELSPCEEE APPSPAEDEH NQNGNLD

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 190-536 of human PDE1B (NP_000915.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PDE1B

Target: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Andere Bezeichnung: PDE1B (PDE1B Produkte)

Synonyme: 63kDa antikoerper, Pde1b1 antikoerper, PDE1B1 antikoerper, PDES1B antikoerper, Aop2 antikoerper, phosphodiesterase 1B, Ca2+-calmodulin dependent antikoerper, phosphodiesterase 1B antikoerper, Pde1b antikoerper, PDE1B antikoerper

Hintergrund: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.,PDE1B,HEL-S-79p,PDE1B1,PDES1B,Cell Biology & Developmental Biology,Apoptosis,PDE1B

Molekulargewicht: 59 kDa/61 kDa

Gen-ID: 5153

UniProt: Q01064

Pathways: Neurotrophin Signalübertragung, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma