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MCM6 Antikörper (AA 562-821)

MCM6 Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3022687
  • Target Alle MCM6 Antikörper anzeigen
    MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))
    Bindungsspezifität
    • 12
    • 9
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 562-821
    Reaktivität
    • 56
    • 23
    • 17
    • 9
    • 7
    • 7
    • 7
    • 4
    • 2
    • 1
    • 1
    Human
    Wirt
    • 46
    • 6
    • 4
    Kaninchen
    Klonalität
    • 51
    • 5
    Polyklonal
    Konjugat
    • 39
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MCM6 Antikörper ist unkonjugiert
    Applikation
    • 43
    • 33
    • 20
    • 15
    • 10
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    Sequenz
    SIDRVYSLDD IRRYLLFARQ FKPKISKESE DFIVEQYKHL RQRDGSGVTK SSWRITVRQL ESMIRLSEAM ARMHCCDEVQ PKHVKEAFRL LNKSIIRVET PDVNLDQEEE IQMEVDEGAG GINGHADSPA PVNGINGYNE DINQESAPKA SLRLGFSEYC RISNLIVLHL RKVEEEEDES ALKRSELVNW YLKEIESEID SEEELINKKR IIEKVIHRLT HYDHVLIELT QAGLKGSTEG SESYEEDPYL VVNPNYLLED
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 562-821 of human MCM6 (NP_005906.2).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze / thaw cycles
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))
    Andere Bezeichnung
    MCM6 (MCM6 Produkte)
    Synonyme
    CG4039 antikoerper, DmMCM6 antikoerper, DmeMCM6 antikoerper, Dmel\\CG4039 antikoerper, MCM6 antikoerper, McM6 antikoerper, fs(1)K1214 antikoerper, mcm6 antikoerper, MCG40308 antikoerper, Mis5 antikoerper, P105MCM antikoerper, Mcmd6 antikoerper, mis5 antikoerper, mmcm6 antikoerper, ASP-l1 antikoerper, D1Wsu22e antikoerper, Minichromosome maintenance 6 antikoerper, DNA replication licensing factor MCM6 antikoerper, minichromosome maintenance complex component 6 antikoerper, minichromosome maintenance complex component 6 L homeolog antikoerper, DNA replication licensing factor mcm-6 antikoerper, Mcm6 antikoerper, TP02_0113 antikoerper, PVX_114735 antikoerper, CMU_027970 antikoerper, MCM6 antikoerper, mcm6.L antikoerper, mcm-6 antikoerper
    Hintergrund
    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, influence lactose intolerance in early adulthood.,MCM6,MCG40308,Mis5,P105MCM,Epigenetics & Nuclear Signaling,MCM6
    Molekulargewicht
    92 kDa
    Gen-ID
    4175
    UniProt
    Q14566
    Pathways
    DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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