RENT1/UPF1 Antikörper (AA 270-370)

Produktnummer ABIN3022069

Produktdetails anti-RENT1/UPF1 Antikörper

Target: RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

Bindungsspezifität: AA 270-370

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RENT1/UPF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequenz: KENPSATLED LEKPGVDEEP QHVLLRYEDA YQYQNIFGPL VKLEADYDKK LKESQTQDNI TVRWDLGLNK KRIAYFTLPK TDSDMRLMQG DEICLRYKGD L

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 270-370 of human UPF1/RENT1 (NP_002902.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RENT1/UPF1

Target: RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

Andere Bezeichnung: UPF1 (UPF1 Produkte)

Synonyme: HUPF1 antikoerper, NORF1 antikoerper, RENT1 antikoerper, pNORF1 antikoerper, smg-2 antikoerper, B430202H16Rik antikoerper, PNORF-1 antikoerper, Rent1 antikoerper, Upflp antikoerper, rent1 antikoerper, wu:fi40f07 antikoerper, wu:fj48a01 antikoerper, zgc:55472 antikoerper, Tb05.3C6.50 antikoerper, AO090012000584 antikoerper, hupf1 antikoerper, norf1 antikoerper, pnorf1 antikoerper, upf1 antikoerper, UPF1, RNA helicase and ATPase antikoerper, UPF1 regulator of nonsense transcripts homolog (yeast) antikoerper, upf1 regulator of nonsense transcripts homolog (yeast) antikoerper, regulator of nonsense transcripts 1 antikoerper, Regulator of nonsense transcripts 1 antikoerper, UPF1 regulator of nonsense transcripts homolog S homeolog antikoerper, UPF1 antikoerper, Upf1 antikoerper, upf1 antikoerper, Tc00.1047053511317.30 antikoerper, Tb927.5.2140 antikoerper, TVAG_453890 antikoerper, TVAG_237840 antikoerper, AOR_1_1018194 antikoerper, HPB8_739 antikoerper, smg-2 antikoerper, upf1.S antikoerper

Hintergrund: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants.,UPF1,HUPF1,NORF1,RENT1,pNORF1,smg-2,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Apoptosis,UPF1

Molekulargewicht: 123 kDa/124 kDa

Gen-ID: 5976

UniProt: Q92900

Pathways: SARS-CoV-2 Protein Interaktom