Tissue factor Antikörper

Produktnummer ABIN3021934

Produktdetails anti-Tissue factor Antikörper

Target: Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tissue factor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human F3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C/-80 °C

Details zu Tissue factor

Target: Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))

Andere Bezeichnung: F3 (F3 Produkte)

Synonyme: CD142 antikoerper, TF antikoerper, TFA antikoerper, PRO1557 antikoerper, PRO2086 antikoerper, TFQTL1 antikoerper, f3 antikoerper, AA409063 antikoerper, Cf-3 antikoerper, Cf3 antikoerper, tf antikoerper, zgc:112151 antikoerper, coagulation factor III, tissue factor antikoerper, transferrin antikoerper, coagulation factor IIIa antikoerper, coagulation factor III antikoerper, tissue factor antikoerper, coagulation factor IIIb antikoerper, coagulation factor III (thromboplastin, tissue factor) S homeolog antikoerper, F3 antikoerper, TF antikoerper, f3a antikoerper, tf antikoerper, f3b antikoerper, f3.S antikoerper

Hintergrund: This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Synonyms: TF, TFA, CD142, F3

Gen-ID: 2152

UniProt: P13726

Pathways: Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling