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NRF2 Antikörper (AA 366-605)

NFE2L2 Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3021832
  • Target Alle NRF2 (NFE2L2) Antikörper anzeigen
    NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
    Bindungsspezifität
    • 23
    • 15
    • 9
    • 8
    • 8
    • 7
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 366-605
    Reaktivität
    • 121
    • 57
    • 55
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 114
    • 9
    • 1
    Kaninchen
    Klonalität
    • 104
    • 20
    Polyklonal
    Konjugat
    • 59
    • 10
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NRF2 Antikörper ist unkonjugiert
    Applikation
    • 97
    • 52
    • 31
    • 29
    • 21
    • 18
    • 15
    • 15
    • 14
    • 9
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    Sequenz
    YGDTLLGLSD SEVEELDSAP GSVKQNGPKT PVHSSGDMVQ PLSPSQGQST HVHDAQCENT PEKELPVSPG HRKTPFTKDK HSSRLEAHLT RDELRAKALH IPFPVEKIIN LPVVDFNEMM SKEQFNEAQL ALIRDIRRRG KNKVAAQNCR KRKLENIVEL EQDLDHLKDE KEKLLKEKGE NDKSLHLLKK QLSTLYLEVF SMLRDEDGKP YSPSEYSLQQ TRDGNVFLVP KSKKPDVKKN
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 366-605 of human NRF2 (NP_006155.2).
    Isotyp
    IgG
    Top Product
    Discover our top product NFE2L2 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze / thaw cycles
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Meng, Song, Wang, Li, Liu, Cui: "Propofol induces proliferation partially via downregulation of p53 protein and promotes migration via activation of the Nrf2 pathway in human breast cancer cell line MDA-MB-231." in: Oncology reports, Vol. 37, Issue 2, pp. 841-848, (2017) (PubMed).

    Xu, Zhang, Lu, Deng, Zhao, Zhao, Zhao: "Prevention of Hippocampal Neuronal Damage and Cognitive Function Deficits in Vascular Dementia by Dextromethorphan." in: Molecular neurobiology, Vol. 53, Issue 5, pp. 3494-502, (2016) (PubMed).

  • Target
    NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
    Andere Bezeichnung
    NFE2L2 (NFE2L2 Produkte)
    Synonyme
    Nrf2 antikoerper, nfe2l2 antikoerper, wu:fc15g09 antikoerper, wu:fj67e03 antikoerper, NF-E2R2 antikoerper, NRF2 antikoerper, AI194320 antikoerper, nuclear factor, erythroid 2-like 2a antikoerper, nuclear factor, erythroid 2 like 2 S homeolog antikoerper, nuclear factor, erythroid 2 like 2 antikoerper, nuclear factor, erythroid derived 2, like 2 antikoerper, nuclear factor, erythroid 2-like 2 antikoerper, nfe2l2a antikoerper, nfe2l2.S antikoerper, NFE2L2 antikoerper, Nfe2l2 antikoerper
    Hintergrund
    This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters, many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.,NFE2L2,HEBP1,NRF2,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial Biogenesis,Nucleotide metabolism,Molecular processes,Cardiovascular,Heart,Cardiac metabolism,NFE2L2
    Molekulargewicht
    65 kDa/66 kDa/67 kDa
    Gen-ID
    4780
    UniProt
    Q16236
    Pathways
    ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
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