Calreticulin Antikörper

Produktnummer ABIN3021345

Produktdetails anti-Calreticulin Antikörper

Target: Calreticulin (CALR)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calreticulin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human CALR

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C/-80 °C

Details zu Calreticulin

Target: Calreticulin (CALR)

Andere Bezeichnung: CALR (CALR Produkte)

Synonyme: CRT antikoerper, RO antikoerper, SSA antikoerper, cC1qR antikoerper, crc antikoerper, crt antikoerper, Calregulin antikoerper, CG9429 antikoerper, Clr antikoerper, Dmel\\CG9429 antikoerper, anon-EST:Liang-2.11 antikoerper, anon-EST:Liang-2.17 antikoerper, anon-EST:fe3D7 antikoerper, clone 2.11 antikoerper, clone 2.17 antikoerper, eth antikoerper, potp antikoerper, cc1qr antikoerper, ssa antikoerper, NV19007 antikoerper, CRP55 antikoerper, ERp60 antikoerper, HACBP antikoerper, CHOT1 antikoerper, CHT1 antikoerper, CT1 antikoerper, AA589632 antikoerper, CRTR antikoerper, Creat antikoerper, CCDS1 antikoerper, calrl2 antikoerper, fc66d10 antikoerper, wu:fc66d10 antikoerper, wu:fj50c03 antikoerper, zgc:66153 antikoerper, calreticulin antikoerper, calreticulin L homeolog antikoerper, Calreticulin antikoerper, putative calreticulin antikoerper, solute carrier family 6 member 8 antikoerper, solute carrier family 6 (neurotransmitter transporter, creatine), member 8 antikoerper, CALR antikoerper, calr.L antikoerper, Crt antikoerper, crt antikoerper, CRT antikoerper, Calr antikoerper, calr antikoerper, LMJF_31_2600 antikoerper, Crc antikoerper, Slc6a8 antikoerper, SLC6A8 antikoerper, LOC8269812 antikoerper

Hintergrund: Calcium is a universal signaling molecule involved in many cellular functions such as cell motility, metabolism, protein modification, protein folding and apoptosis. Calcium is stored in the endoplasmic reticulum (ER), where it is buffered by calcium binding chaperones such as calnexin and calreticulin, and is released via the IP3 Receptor. Calreticulin also functions as an ER chaperone that ensures proper folding and quality control of newly synthesized glycoproteins. As such, calreticulin presumably does not alter protein folding but ensures proper timing for efficient folding and subunit assembly. Furthermore, calreticulin retains proteins in non-native conformation within the ER and targets them for degradation.
Synonyms: CALR, CRT, FLJ26680, RO, SSA, cC1qR

Gen-ID: 811

UniProt: P27797

Pathways: Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response