NME1 Antikörper (C-Term)

Produktnummer ABIN3020815

Produktdetails anti-NME1 Antikörper

Target: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NME1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: MLGETNPADS KPGTIRGDFC IQVGRNIIHG SDSVESAEKE IGLWFHPEEL VDYTSCAQNW IYE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 90 to the C-terminus of human NME1/NM23A (NP_000260.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-NME1 Antikörper (ABIN3020815)

Wang, Bai, Cheng, Ihsan, Zhu, Wang, Tao, Chen, Dai, Liu, Yuan: "Genomic and proteomic analysis of the inhibition of synthesis and secretion of aldosterone hormone induced by quinocetone in NCI-H295R cells." in: Toxicology, Vol. 350-352, pp. 1-14, (2017) (PubMed).

Details zu NME1

Target: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Andere Bezeichnung: NME1 (NME1 Produkte)

Synonyme: AWD antikoerper, GAAD antikoerper, NB antikoerper, NBS antikoerper, NDKA antikoerper, NDPK-A antikoerper, NDPKA antikoerper, NM23 antikoerper, NM23-H1 antikoerper, AL024257 antikoerper, NM23-M1 antikoerper, NM23A antikoerper, NDPK-Z1 antikoerper, NM23-B antikoerper, NM23-Z1 antikoerper, ndpkz1 antikoerper, nm23b antikoerper, nme1 antikoerper, nme2 antikoerper, nme2b1 antikoerper, NME1 antikoerper, NME1-NME2 antikoerper, NM23-C1 antikoerper, ndpk-b antikoerper, ndpkb antikoerper, nm23-h2 antikoerper, nm23ndk antikoerper, puf antikoerper, NBR-A antikoerper, NBR-B antikoerper, NME1-1 antikoerper, nm23ndk-a antikoerper, NDK I antikoerper, NDPK I antikoerper, T30A10.80 antikoerper, T30A10_80 antikoerper, NDP kinase I antikoerper, NME/NM23 nucleoside diphosphate kinase 1 antikoerper, NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1 antikoerper, non-metastatic cells 1, protein (NM23A) expressed in antikoerper, NME/NM23 nucleoside diphosphate kinase 2 S homeolog antikoerper, NME/NM23 nucleoside diphosphate kinase 2 L homeolog antikoerper, nucleoside diphosphate kinase antikoerper, nucleoside diphosphate kinase 1 antikoerper, NME1 antikoerper, Nme1 antikoerper, nme2b.1 antikoerper, nme2.S antikoerper, nme2.L antikoerper, LOC547870 antikoerper, NDPK1 antikoerper, LOC107790563 antikoerper

Hintergrund: This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.,NME1,AWD,GAAD,NB,NBS,NDKA,NDPK-A,NDPKA,NM23,NM23-H1,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,Neurodegenerative Diseases Markers,Other Neurological disorders,Cerebralvascular accident-CVA,NME1

Molekulargewicht: 17 kDa/19 kDa/30 kDa

Gen-ID: 4830

UniProt: P15531

Pathways: Apoptose, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process