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IKKi/IKKe Antikörper (AA 495-716)

IKBKE Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3020771
  • Target Alle IKKi/IKKe (IKBKE) Antikörper anzeigen
    IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))
    Bindungsspezifität
    • 15
    • 10
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 495-716
    Reaktivität
    • 66
    • 26
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 76
    • 6
    Kaninchen
    Klonalität
    • 67
    • 15
    Polyklonal
    Konjugat
    • 34
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IKKi/IKKe Antikörper ist unkonjugiert
    Applikation
    • 66
    • 38
    • 21
    • 16
    • 16
    • 14
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    LRSRLRTLAE VLSRCSQNIT ETQESLSSLN RELVKSRDQV HEDRSIQQIQ CCLDKMNFIY KQFKKSRMRP GLGYNEEQIH KLDKVNFSHL AKRLLQVFQE ECVQKYQASL VTHGKRMRVV HETRNHLRLV GCSVAACNTE AQGVQESLSK LLEELSHQLL QDRAKGAQAS PPPIAPYPSP TRKDLLLHMQ ELCEGMKLLA SDLLDNNRII ERLNRVPAPP DV
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 495-716 of human IKKepsilon (NP_054721.1).
    Isotyp
    IgG
    Top Product
    Discover our top product IKBKE Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze / thaw cycles
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • He, Ma, Tian, Wei, Zhu, Li, Zhang, Wang, Zhang, Zhong: "ERRα negatively regulates type I interferon induction by inhibiting TBK1-IRF3 interaction." in: PLoS pathogens, Vol. 13, Issue 6, pp. e1006347, (2017) (PubMed).

    Gao, Yang, Yuan, Huang, Xu, Mao, Yuan, Bi: "TNFα-YAP/p65-HK2 axis mediates breast cancer cell migration." in: Oncogenesis, Vol. 6, Issue 9, pp. e383, (2017) (PubMed).

  • Target
    IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))
    Andere Bezeichnung
    IKBKE (IKBKE Produkte)
    Synonyme
    zgc:100844 antikoerper, IKBKE antikoerper, MGC130907 antikoerper, IKK-E antikoerper, IKK-i antikoerper, IKKE antikoerper, IKKI antikoerper, AW558201 antikoerper, IKKepsilon antikoerper, Ikki antikoerper, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon antikoerper, inhibitor of nuclear factor kappa B kinase subunit epsilon antikoerper, inhibitor of nuclear factor kappa B kinase subunit epsilon L homeolog antikoerper, inhibitor of kappaB kinase epsilon antikoerper, IKBKE antikoerper, ikbke antikoerper, ikbke.L antikoerper, Ikbke antikoerper
    Hintergrund
    IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30 % of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009],IKBKE,IKK-E,IKK-i,IKKE,IKKI,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Death Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,IKBKE
    Molekulargewicht
    70 kDa/80 kDa
    Gen-ID
    9641
    UniProt
    Q14164
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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