BAK1 Antikörper (AA 62-112)
-
- Target Alle BAK1 Antikörper anzeigen
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
-
Bindungsspezifität
- AA 62-112
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser BAK1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
- Sequenz
- TLPLQPSSTM GQVGRQLAII GDDINRRYDS EFQTMLQHLQ PTAENAYEYF T
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 62-112 of human Bak (NP_001179.1).
- Isotyp
- IgG
- Top Product
- Discover our top product BAK1 Primärantikörper
-
-
- Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid freeze / thaw cycles
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
- Andere Bezeichnung
- Bak1 (BAK1 Produkte)
- Hintergrund
- The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.,BAK1,BAK,BAK-LIKE,BCL2L7,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Bak1
- Molekulargewicht
- 16 kDa/23 kDa
- Gen-ID
- 578
- UniProt
- Q16611
- Pathways
- Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
-