Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

LRP5 Antikörper (AA 1000-1250)

LRP5 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1513164
  • Target Alle LRP5 Antikörper anzeigen
    LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
    Bindungsspezifität
    • 17
    • 15
    • 15
    • 8
    • 7
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1000-1250
    Reaktivität
    • 59
    • 45
    • 22
    • 1
    • 1
    Human
    Wirt
    • 67
    • 5
    • 1
    • 1
    Kaninchen
    Klonalität
    • 70
    • 4
    Polyklonal
    Konjugat
    • 26
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser LRP5 Antikörper ist unkonjugiert
    Applikation
    • 43
    • 38
    • 26
    • 20
    • 13
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    IKRAKDDGTQ PFVLTSLSQG QNPDRQPHDL SIDIYSRTLF WTCEATNTIN VHRLSGEAMG VVLRGDRDKP RAIVVNAERG YLYFTNMQDR AAKIERAALD GTEREVLFTT GLIRPVALVV DNTLGKLFWV DADLKRIESC DLSGANRLTL EDANIVQPLG LTILGKHLYW IDRQQQMIER VEKTTGDKRT RIQGRVAHLT GIHAVEEVSL EEFSAHPCAR DNGGCSHICI AKGDGTPRCS CPVHLVLLQN L
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1250 of human LRP5 (NP_002326.2).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze / thaw cycles
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Fu, Wang, Wan, Lin, Chang, Han: "Wnt5a mediated canonical Wnt signaling pathway activation in orthodontic tooth movement: possible role in the tension force-induced bone formation." in: Journal of molecular histology, Vol. 47, Issue 5, pp. 455-66, (2017) (PubMed).

  • Target
    LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
    Andere Bezeichnung
    LRP5 (LRP5 Produkte)
    Synonyme
    Xlrp5 antikoerper, bmnd1 antikoerper, evr1 antikoerper, evr4 antikoerper, hbm antikoerper, lr3 antikoerper, lrp5-A antikoerper, lrp7 antikoerper, oppg antikoerper, ops antikoerper, opta1 antikoerper, vbch2 antikoerper, LRP5 antikoerper, LRP6 antikoerper, BMND1 antikoerper, EVR1 antikoerper, EVR4 antikoerper, HBM antikoerper, LR3 antikoerper, LRP7 antikoerper, OPPG antikoerper, OPS antikoerper, OPTA1 antikoerper, VBCH2 antikoerper, mKIAA4142 antikoerper, low-density lipoprotein receptor-related protein 5 antikoerper, LDL receptor related protein 5 antikoerper, LDL receptor related protein 5 L homeolog antikoerper, low density lipoprotein receptor-related protein 5 antikoerper, LDL receptor related protein 5 like antikoerper, LOC100147353 antikoerper, LRP5 antikoerper, lrp5.L antikoerper, lrp5 antikoerper, Lrp5 antikoerper, LRP5L antikoerper
    Hintergrund
    This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants.,LRP5,BMND1,EVR1,EVR4,HBM,LR3,LRP-5,LRP7,OPPG,OPS,OPTA1,VBCH2,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Signal Transduction,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,Extracellular Matrix,Bone,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Neuroscience,Stem Cells,Cardiovascular,Lipids,LRP5
    Molekulargewicht
    179 kDa
    Gen-ID
    4041
    UniProt
    O75197
    Pathways
    WNT Signalweg, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
Sie sind hier:
Kundenservice