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ATF2 Antikörper (pThr71)

ATF2 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3019452
  • Target Alle ATF2 Antikörper anzeigen
    ATF2 (Activating Transcription Factor 2 (ATF2))
    Bindungsspezifität
    • 49
    • 36
    • 26
    • 26
    • 24
    • 24
    • 23
    • 23
    • 15
    • 15
    • 14
    • 14
    • 12
    • 10
    • 9
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr71
    Reaktivität
    • 295
    • 229
    • 206
    • 16
    • 12
    • 11
    • 8
    • 7
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 327
    • 12
    • 2
    • 1
    Kaninchen
    Klonalität
    • 313
    • 29
    Polyklonal
    Konjugat
    • 154
    • 20
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 13
    • 12
    • 9
    • 8
    • 8
    • 8
    • 8
    • 5
    • 4
    Dieser ATF2 Antikörper ist unkonjugiert
    Applikation
    • 241
    • 118
    • 112
    • 111
    • 76
    • 61
    • 59
    • 35
    • 33
    • 22
    • 15
    • 10
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    TPTPT
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Phosphorylated Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic phosphorylated peptide around T71 of human ATF2 (NP_001871.2).
    Isotyp
    IgG
    Top Product
    Discover our top product ATF2 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:1000,IHC,1:50 - 1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Zhang, He, Wang, Zhang, Huang, Xiong, Yan, Wu, Ren, Han, Liu, Qian, Du: "Virus-Triggered ATP Release Limits Viral Replication through Facilitating IFN-β Production in a P2X7-Dependent Manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 4, pp. 1372-1381, (2017) (PubMed).

  • Target
    ATF2 (Activating Transcription Factor 2 (ATF2))
    Andere Bezeichnung
    ATF2 (ATF2 Produkte)
    Synonyme
    CRE-BP1 antikoerper, CREB2 antikoerper, HB16 antikoerper, TREB7 antikoerper, CG12850 antikoerper, CG3749 antikoerper, dATF-2 antikoerper, DmelCG30420 antikoerper, CG30420 antikoerper, CHN1 antikoerper, Atf-2 antikoerper, CRE-BP antikoerper, Creb2 antikoerper, D130078H02Rik antikoerper, D18875 antikoerper, Tg(Gzma-Klra1)7Wum antikoerper, mXBP antikoerper, atf2-A antikoerper, atf2l antikoerper, activating transcription factor 2 antikoerper, Activating transcription factor-2 antikoerper, activating transcription factor 2 S homeolog antikoerper, ATF2 antikoerper, Atf-2 antikoerper, Atf2 antikoerper, atf2.S antikoerper, atf2 antikoerper
    Hintergrund
    This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene,CRE-BP1,CREB-2,CREB2,HB16,TREB7,ATF2,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-JNK Signaling Pathway,MAPK-P38 Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Protein phosphorylation,ATF2
    Molekulargewicht
    13- 15 kDa/23-24 kDa/35-54 kDa
    Gen-ID
    1386
    UniProt
    P15336
    Pathways
    MAPK Signalweg, RTK Signalweg, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
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