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PSMD2 Antikörper (AA 1-260)

PSMD2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3015813
  • Target Alle PSMD2 Antikörper anzeigen
    PSMD2 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 2 (PSMD2))
    Bindungsspezifität
    • 12
    • 7
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-260
    Reaktivität
    • 51
    • 14
    • 12
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 43
    • 7
    • 1
    Kaninchen
    Klonalität
    • 46
    • 5
    Polyklonal
    Konjugat
    • 31
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PSMD2 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 28
    • 11
    • 10
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    MEEGGRDKAP VQPQQSPAAA PGGTDEKPSG KERRDAGDKD KEQELSEEDK QLQDELEMLV ERLGEKDTSL YRPALEELRR QIRSSTTSMT SVPKPLKFLR PHYGKLKEIY ENMAPGENKR FAADIISVLA MTMSGERECL KYRLVGSQEE LASWGHEYVR HLAGEVAKEW QELDDAEKVQ REPLLTLVKE IVPYNMAHNA EHEACDLLME IEQVDMLEKD IDENAYAKVC LYLTSCVNYV PEPENSALLR CALGVFRKFS
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PSMD2 (NP_002799.3).
    Isotyp
    IgG
    Top Product
    Discover our top product PSMD2 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PSMD2 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 2 (PSMD2))
    Andere Bezeichnung
    PSMD2 (PSMD2 Produkte)
    Synonyme
    DDBDRAFT_0192101 antikoerper, DDBDRAFT_0232978 antikoerper, DDB_0192101 antikoerper, DDB_0232978 antikoerper, zgc:65921 antikoerper, MGC83233 antikoerper, psmd2 antikoerper, MGC97650 antikoerper, PSMD2 antikoerper, P97 antikoerper, RPN1 antikoerper, S2 antikoerper, TRAP2 antikoerper, 9430095H01Rik antikoerper, AA407121 antikoerper, TEG-190 antikoerper, Tex190 antikoerper, 26S proteasome non-ATPase regulatory subunit 2 antikoerper, 26S proteasome regulatory subunit S2 antikoerper, proteasome 26S subunit, non-ATPase 2 antikoerper, proteasome 26S subunit, non-ATPase 2 L homeolog antikoerper, proteasome 26S subunit, non-ATPase 2 S homeolog antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 antikoerper, psmD2 antikoerper, NAEGRDRAFT_83014 antikoerper, DICPUDRAFT_55026 antikoerper, psmd2 antikoerper, psmd2.L antikoerper, psmd2.S antikoerper, PSMD2 antikoerper, Psmd2 antikoerper
    Hintergrund
    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1. Alternative splicing results in multiple transcript variants of this gene.,PSMD2,P97,RPN1,S2,TRAP2,Cell Biology & Developmental Biology,Ubiquitin,PSMD2
    Molekulargewicht
    82 kDa/85 kDa/100 kDa
    Gen-ID
    5708
    UniProt
    Q13200
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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