Angiotensin II Type-1 Receptor Antikörper

Produktnummer ABIN289368

Produktdetails anti-Angiotensin II Type-1 Receptor Antikörper

Target: Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

Reaktivität: Ratte

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser Angiotensin II Type-1 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Spezifität: The 10 aa peptide is 100%, identical in Mouse, Ovine rat, human, Pig,and rabbit.

Kreuzreaktivität (Details): This 10 AA immunogenic peptide is 100 % identical in mouse, rat, human, ovine, pig, dog, chimpanzee and chicken. The sequence is the same in all AT II receptor isoforms (Type 1a, 1b, and 1c).

Aufreinigung: Affinity chromatography purified

Immunogen: AGTR1 antibody was raised in chicken using 10-aa peptide from rat AT-II type 1 as the immunogen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10,000-1:100,000, WB: 1-10 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in PBS to a concentration of 1 mg/mL

Konzentration: Lot specific

Buffer: Lyophilized from PBS with 0.1 % BSA.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Referenzen für anti-Angiotensin II Type-1 Receptor Antikörper (ABIN289368)

Walch, Carreño, Cunningham: "Intracerebroventricular losartan infusion modulates angiotensin II type 1 receptor expression in the subfornical organ and drinking behaviour in bile-duct-ligated rats." in: Experimental physiology, Vol. 98, Issue 4, pp. 922-33, (2013) (PubMed).

Details zu Angiotensin II Type-1 Receptor

Target: Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

Andere Bezeichnung: AGTR1 (AGTR1 Produkte)

Synonyme: AG2S antikoerper, AGTR1A antikoerper, AGTR1B antikoerper, AT1 antikoerper, AT1AR antikoerper, AT1B antikoerper, AT1BR antikoerper, AT1R antikoerper, AT2R1 antikoerper, AT2R1A antikoerper, AT2R1B antikoerper, HAT1R antikoerper, 1810074K20Rik antikoerper, AI551199 antikoerper, AT1a antikoerper, Agtr-1a antikoerper, Agtr1 antikoerper, Angtr-1a antikoerper, AT1A antikoerper, XAT-1 antikoerper, agtr1-A antikoerper, agtr1.2 antikoerper, AT1-R antikoerper, at1 antikoerper, AGTR1 antikoerper, Agtr-1b antikoerper, Angtr-1b antikoerper, agtr1 antikoerper, agtr1-a antikoerper, agtr1-b antikoerper, xAT antikoerper, angiotensin II receptor type 1 antikoerper, angiotensin II receptor, type 1a antikoerper, angiotensin II receptor type 1 S homeolog antikoerper, uncharacterized AGTR1 antikoerper, angiotensin II receptor, type 1b antikoerper, angiotensin II receptor type 1 L homeolog antikoerper, AGTR1 antikoerper, Agtr1a antikoerper, agtr1.S antikoerper, Agtr1 antikoerper, Agtr1b antikoerper, agtr1.L antikoerper

Hintergrund: Angiotensin II receptor, type 1 or AT1 receptor is an angiotensin receptor. It has vasopressor effects and regulates aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. Angiotensin II receptor antagonists are drugs indicated for hypertension, diabetic nephropathy and congestive heart failure.

Pathways: JAK-STAT Signalweg, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour