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UVRAG Antikörper (C-Term) (FITC)

UVRAG Reaktivität: Human WB, IF, ICC Wirt: Kaninchen Polyclonal FITC
Produktnummer ABIN2868804
  • Target Alle UVRAG Antikörper anzeigen
    UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
    Bindungsspezifität
    • 14
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 63
    • 38
    • 30
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 59
    • 4
    Kaninchen
    Klonalität
    • 61
    • 2
    Polyklonal
    Konjugat
    • 27
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UVRAG Antikörper ist konjugiert mit FITC
    Applikation
    • 56
    • 21
    • 13
    • 12
    • 12
    • 10
    • 9
    • 9
    • 6
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Predicted molecular weight at ~78.1 kDa. Observed molecular weights in the 75-90 kDa range.
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Peptide Affinity Purified
    Immunogen
    Synthetic peptide from the C-terminal of human UVRAG
    Top Product
    Discover our top product UVRAG Primärantikörper
  • Applikationshinweise
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    A 1:1000 dilution of ABIN2868804 was sufficient for detection of UVRAG on 293T Rapamycin treated lysates using Goat anti-rabbit IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
    Andere Bezeichnung
    UVRAG (UVRAG Produkte)
    Synonyme
    DHTX antikoerper, VPS38 antikoerper, p63 antikoerper, 9530039D02Rik antikoerper, AI648770 antikoerper, BB124205 antikoerper, Uvrag1 antikoerper, Uvragl antikoerper, zgc:56164 antikoerper, uvrag antikoerper, MGC81810 antikoerper, UVRAG antikoerper, MGC131135 antikoerper, CG6116 antikoerper, Dmel\\CG6116 antikoerper, UV radiation resistance associated antikoerper, UV radiation resistance associated gene antikoerper, UV radiation resistance associated S homeolog antikoerper, UV radiation resistance associated L homeolog antikoerper, UV-resistance associated gene antikoerper, UVRAG antikoerper, Uvrag antikoerper, uvrag antikoerper, uvrag.S antikoerper, uvrag.L antikoerper
    Hintergrund
    UVRAG (UV radiation resistance-associated gene) is associated with the Beclin-1/PI3KC3 complex and promotes PI3KC3 enzymatic activity and autophagy, while suppressing proliferation (1). Beclin-1 binding to UVRAG promotes both autophagosome maturation and endocytic trafficking (2). UVRAG is also a potential tumor suppressor protein with frameshift mutations observed in colon and gastric carcinomas (3-4). It is highly expressed in the brain, lung, kidney and liver.
    Gen-ID
    7405
    NCBI Accession
    NP_003360
    UniProt
    Q9P2Y5
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