PP5 Antikörper (Biotin)

Produktnummer ABIN2868711

Produktdetails anti-PP5 Antikörper (Biotin)

Target: PP5 (PPP5C) (Protein Phosphatase 5, Catalytic Subunit (PPP5C))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PP5 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Detects ~58 kDa.

Kreuzreaktivität: Human

Aufreinigung: Protein G Purified

Immunogen: Full length human PP5 protein

Klon: 12F7

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Kommentare:

1 μg/ml of ABIN2868711 was sufficient for detection of PP5 in 15 μg of human A431 lysates by ECL analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu PP5

Target: PP5 (PPP5C) (Protein Phosphatase 5, Catalytic Subunit (PPP5C))

Andere Bezeichnung: PP5 (PPP5C Produkte)

Synonyme: PP5 antikoerper, PPP5 antikoerper, PPT antikoerper, AU020526 antikoerper, pp5 antikoerper, MGC89961 antikoerper, fc83f08 antikoerper, im:7146608 antikoerper, wu:fc83f08 antikoerper, zgc:110801 antikoerper, PPP5C antikoerper, protein phosphatase 5 catalytic subunit antikoerper, protein phosphatase 5, catalytic subunit antikoerper, protein phosphatase 5, catalytic subunit S homeolog antikoerper, serine/threonine-protein phosphatase 5 antikoerper, PPP5C antikoerper, Ppp5c antikoerper, ppp5c.S antikoerper, ppp5c antikoerper, LOC592155 antikoerper, LOC100513542 antikoerper, LOC100564151 antikoerper, LOC100186268 antikoerper, LOC100208775 antikoerper

Hintergrund: Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues, potentially playing a role in the regulation of cell growth and differentiation. PP5 or PPT is predominantly a nuclear protein and interacts with CDC16 and CDC27. It is found in association with several proteins that influence intracellular signlaing-cascades intitiated by hormones (glucocorticoids) or cellular stress (hypoxia, oxidative stress and DNA Damage). It phosphorylates serine residues of skeletal muscle phosphorylase and histone H1. It may also be involved in mitosis and RNA biogenesis regulation (1,2).

Gen-ID: 5536

NCBI Accession: NP_006238

UniProt: P53041