ZC3H8 Antikörper
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- Target Alle ZC3H8 Antikörper anzeigen
- ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ZC3H8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Produktmerkmale
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Rabbit polyclonal antibody to ZC3H8 (zinc finger CCCH-type containing 8)
ZC3H8 antibody [N1C3] - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human ZC3H8. The exact sequence is proprietary.
- Isotyp
- IgG
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- Applikationshinweise
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Positive Control: A431 , HepG2 , Raji
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.84 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))
- Andere Bezeichnung
- zinc finger CCCH-type containing 8 (ZC3H8 Produkte)
- Synonyme
- Zc3hdc8 antikoerper, DKFZp459D018 antikoerper, AU020882 antikoerper, E130108N08Rik antikoerper, Fliz1 antikoerper, ZC3HDC8 antikoerper, zinc finger CCCH type containing 8 antikoerper, zinc finger CCCH-type containing 8 antikoerper, Zc3h8 antikoerper, ZC3H8 antikoerper
- Hintergrund
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Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
Cellular Localization: Nucleus - Molekulargewicht
- 34 kDa
- Gen-ID
- 84524
- UniProt
- Q8N5P1
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