DIABLO Antikörper
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- Target Alle DIABLO Antikörper anzeigen
- DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DIABLO Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
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Rabbit Polyclonal antibody to Smac (diablo homolog (Drosophila))
Diablo antibody [N1C3] - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human Diablo. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product DIABLO Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Positive Control: A431 , mouse testis
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
- Andere Bezeichnung
- diablo IAP-binding mitochondrial protein (DIABLO Produkte)
- Synonyme
- smac antikoerper, smac3 antikoerper, diablo-s antikoerper, 0610041G12Rik antikoerper, 1700006L01Rik antikoerper, AU040403 antikoerper, Smac antikoerper, DFNA64 antikoerper, SMAC antikoerper, DBO antikoerper, XSmac antikoerper, diablo, IAP-binding mitochondrial protein antikoerper, diablo IAP-binding mitochondrial protein antikoerper, diablo, IAP-binding mitochondrial protein L homeolog antikoerper, diablo antikoerper, Diablo antikoerper, DIABLO antikoerper, diablo.L antikoerper
- Hintergrund
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This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein.
Cellular Localization: Mitochondrion - Molekulargewicht
- 27 kDa
- Gen-ID
- 56616
- UniProt
- Q9NR28
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
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