WNT11 Antikörper (Center)

Produktnummer ABIN2856232

Produktdetails anti-WNT11 Antikörper

Target: WNT11 (Wingless-Type MMTV Integration Site Family, Member 11 (WNT11))

Bindungsspezifität: Center

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WNT11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Kreuzreaktivität: Huhn, Ratte (Rattus), Xenopus laevis, Rind (Kuh)

Kreuzreaktivität (Details): Chicken (85 %), Rat (96 %), Xenopus laevis (81 %), Bovine (98 %)

Produktmerkmale: Rabbit Polyclonal antibody to WNT11 (wingless-type MMTV integration site family, member 11)
WNT11 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human WNT11. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* Immunohistochemistry Assay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* ImmunohistochemistryAssay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: 293T , A431 , HeLa , HepG2 , mouse heart

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS, 20 % Glycerol ( pH 7). 0.025 % ProClin 300 was added as a preservative.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-WNT11 Antikörper (ABIN2856232)

Glaeser, Urban, Fenech, Voloshanenko, Kranz, Lari, Christianson, Boutros: "ERAD-dependent control of the Wnt secretory factor Evi." in: The EMBO journal, Vol. 37, Issue 4, (2018) (PubMed).

Jain, Noordam, Hoshi, Vallania, Conrad: "Validating single-cell genomics for the study of renal development." in: Kidney international, Vol. 86, Issue 5, pp. 1049-55, (2015) (PubMed).

Details zu WNT11

Target: WNT11 (Wingless-Type MMTV Integration Site Family, Member 11 (WNT11))

Andere Bezeichnung: WNT11 (WNT11 Produkte)

Synonyme: HWNT11 antikoerper, Wnt11r antikoerper, Xwnt11 antikoerper, Xwnt-11 antikoerper, wnt11-r antikoerper, XWnt-11 antikoerper, wnt11b antikoerper, wnt11b-2 antikoerper, Slb/Wnt11 antikoerper, cb748 antikoerper, slb antikoerper, Wnt12 antikoerper, WNT11 antikoerper, wnt-11 antikoerper, xwnt11 antikoerper, Wnt family member 11 antikoerper, wingless-type MMTV integration site family member 11 L homeolog antikoerper, wingless-type MMTV integration site family, member 11B antikoerper, wingless-type MMTV integration site family, member 11 antikoerper, protein Wnt-11-like antikoerper, wingless-type MMTV integration site family, member 10B antikoerper, wingless-type MMTV integration site family, member 11B L homeolog antikoerper, WNT11 antikoerper, Wnt11 antikoerper, wnt11.L antikoerper, wnt11b antikoerper, wnt11 antikoerper, LOC100229189 antikoerper, Wnt10b antikoerper, wnt11b.L antikoerper

Hintergrund: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 97 % , 85 %, and 63 % amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome.

Cellular Localization: Secreted , extracellular space , extracellular matrix

Molekulargewicht: 39 kDa

Gen-ID: 7481

Pathways: WNT Signalweg, Cell-Cell Junction Organization