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POLRMT Antikörper (Center)

POLRMT Reaktivität: Human, Maus WB, IF, ICC, IHC (p), CUT&RUN Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2856044
  • Target Alle POLRMT Antikörper anzeigen
    POLRMT (Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT))
    Bindungsspezifität
    • 15
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reaktivität
    • 29
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 23
    • 5
    • 1
    Kaninchen
    Klonalität
    • 26
    • 3
    Polyklonal
    Konjugat
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser POLRMT Antikörper ist unkonjugiert
    Applikation
    • 21
    • 13
    • 13
    • 11
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Cleavage Under Targets and Release Using Nuclease (CUT&RUN)
    Produktmerkmale
    Rabbit Polyclonal antibody to mtRNA polymerase (polymerase (RNA) mitochondrial (DNA directed))
    mtRNA polymerase antibody [N2N3]
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human mtRNA polymerase. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product POLRMT Primärantikörper
  • Applikationshinweise
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Kommentare

    Positive Control: HepG2

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.31 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Kasinathan, Henikoff: "Non-B-Form DNA Is Enriched at Centromeres." in: Molecular biology and evolution, Vol. 35, Issue 4, pp. 949-962, (2019) (PubMed).

    Thakur, Henikoff: "Unexpected conformational variations of the human centromeric chromatin complex." in: Genes & development, Vol. 32, Issue 1, pp. 20-25, (2018) (PubMed).

    Sobek, Dalla Rosa, Pommier, Bornholz, Kalfalah, Zhang, Wiesner, von Kleist-Retzow, Hillebrand, Schaal, Mielke, Christensen, Boege: "Negative regulation of mitochondrial transcription by mitochondrial topoisomerase I." in: Nucleic acids research, Vol. 41, Issue 21, pp. 9848-57, (2014) (PubMed).

  • Target
    POLRMT (Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT))
    Andere Bezeichnung
    MtRNA Polymerase (POLRMT Produkte)
    Synonyme
    polrmt-a antikoerper, mtRPO antikoerper, wu:fb73g10 antikoerper, si:dkeyp-74c5.5 antikoerper, POLRMT antikoerper, APOLMT antikoerper, MTRNAP antikoerper, MTRPOL antikoerper, h-mtRPOL antikoerper, 1110018N15Rik antikoerper, 4932416K13 antikoerper, RNA polymerase mitochondrial antikoerper, polymerase (RNA) mitochondrial (DNA directed) L homeolog antikoerper, polymerase (RNA) mitochondrial (DNA directed) antikoerper, Polrmt antikoerper, polrmt.L antikoerper, polrmt antikoerper, POLRMT antikoerper
    Hintergrund
    This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes.

    Cellular Localization: Mitochondrion
    Molekulargewicht
    139 kDa
    Gen-ID
    5442
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