CLPP Antikörper (C-Term)

Produktnummer ABIN2855887

Produktdetails anti-CLPP Antikörper

Target: CLPP (ClpP Caseinolytic Peptidase, ATP-Dependent, Proteolytic Subunit Homolog (E. Coli) (CLPP))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLPP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Produktmerkmale: Rabbit Polyclonal antibody to CLPP (ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli))
CLPP antibody [C2C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CLPP. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: 293T , A431 , H1299 , HepG2 , Molt-4 , Raji , Jurkat , NCI-H929

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-CLPP Antikörper (ABIN2855887)

Sen, Rastogi, Nath, Shasthry, Pamecha, Pandey, Gupta, Sarin, Trehanpati, Ramakrishna: "Senescent Hepatocytes in Decompensated Liver Show Reduced UPRMT and Its Key Player, CLPP, Attenuates Senescence In Vitro." in: Cellular and molecular gastroenterology and hepatology, Vol. 8, Issue 1, pp. 73-94, (2020) (PubMed).

Details zu CLPP

Target: CLPP (ClpP Caseinolytic Peptidase, ATP-Dependent, Proteolytic Subunit Homolog (E. Coli) (CLPP))

Andere Bezeichnung: CLPP (CLPP Produkte)

Synonyme: CLPP antikoerper, MGC130667 antikoerper, AU019820 antikoerper, D17Wsu160e antikoerper, PRLTS3 antikoerper, caseinolytic mitochondrial matrix peptidase proteolytic subunit antikoerper, caseinolytic mitochondrial matrix peptidase proteolytic subunit L homeolog antikoerper, ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog antikoerper, CLPP antikoerper, clpp.L antikoerper, clpp antikoerper, Clpp antikoerper

Hintergrund: The protein encoded by this gene belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. The protein is transported into mitochondrial matrix and is associated with the inner mitochondrial membrane.

Cellular Localization: Mitochondrion

Molekulargewicht: 30 kDa

Gen-ID: 8192