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CD27 Antikörper

CD27 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855821
  • Target Alle CD27 Antikörper anzeigen
    CD27 (CD27 Molecule (CD27))
    Reaktivität
    • 188
    • 61
    • 46
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 103
    • 90
    • 15
    • 11
    • 3
    • 1
    Kaninchen
    Klonalität
    • 134
    • 87
    • 2
    Polyklonal
    Konjugat
    • 73
    • 23
    • 22
    • 14
    • 11
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD27 Antikörper ist unkonjugiert
    Applikation
    • 146
    • 83
    • 51
    • 35
    • 33
    • 20
    • 16
    • 13
    • 13
    • 13
    • 11
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human
    Produktmerkmale
    Rabbit Polyclonal antibody to CD27 (CD27 Molecule)
    CD27 antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human CD27. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product CD27 Primärantikörper
  • Applikationshinweise
    WB: 1:5000-1:20000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: K562

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    CD27 (CD27 Molecule (CD27))
    Andere Bezeichnung
    CD27 molecule (CD27 Produkte)
    Synonyme
    TNFRSF7 antikoerper, S152 antikoerper, Tnfrsf7 antikoerper, Tp55 antikoerper, S152. LPFS2 antikoerper, T14 antikoerper, CD27 molecule antikoerper, CD27 antigen antikoerper, CD27 antikoerper, Cd27 antikoerper
    Hintergrund
    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

    Cellular Localization: Membrane
    Molekulargewicht
    29 kDa
    Gen-ID
    939
    UniProt
    P26842
    Pathways
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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