PSMC6 Antikörper

Produktnummer ABIN2855808

Produktdetails anti-PSMC6 Antikörper

Target: PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to PSMC6 (proteasome (prosome, macropain) 26S subunit, ATPase, 6)
PSMC6 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PSMC6. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Mouse brain , 293T

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu PSMC6

Target: PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))

Andere Bezeichnung: proteasome 26S subunit, ATPase 6 (PSMC6 Produkte)

Synonyme: DDBDRAFT_0186051 antikoerper, DDBDRAFT_0232968 antikoerper, DDB_0186051 antikoerper, DDB_0232968 antikoerper, fb20g04 antikoerper, wu:fb20g04 antikoerper, wu:fc85c10 antikoerper, cadp44 antikoerper, sug2 antikoerper, PSMC6 antikoerper, psmc6-a antikoerper, NV13405 antikoerper, CADP44 antikoerper, P44 antikoerper, SUG2 antikoerper, p42 antikoerper, 2300001E01Rik antikoerper, AI451058 antikoerper, 26S protease regulatory subunit S10B antikoerper, 26S proteasome regulatory subunit 10B antikoerper, proteasome 26S subunit, ATPase 6 antikoerper, proteasome 26S subunit, ATPase 6 L homeolog antikoerper, 26S protease regulatory subunit 10B antikoerper, proteasome 26S subunit, ATPase 6 S homeolog antikoerper, proteasome (prosome, macropain) 26S subunit, ATPase, 6 antikoerper, ATEG_02903 antikoerper, HCAG_04181 antikoerper, LOC5565051 antikoerper, EDI_289460 antikoerper, CpipJ_CPIJ003334 antikoerper, EHI_194070 antikoerper, PTRG_02716 antikoerper, BDBG_01801 antikoerper, psmC6 antikoerper, MCYG_07206 antikoerper, PITG_00229 antikoerper, VDBG_04729 antikoerper, MGYG_04704 antikoerper, TERG_01608 antikoerper, DICPUDRAFT_97252 antikoerper, Tsp_02519 antikoerper, prs10 antikoerper, LOC100282100 antikoerper, Psmc6 antikoerper, psmc6 antikoerper, psmc6.L antikoerper, PSMC6 antikoerper, LOC693577 antikoerper, psmc6.S antikoerper, LOC100117671 antikoerper

Hintergrund: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.

Cellular Localization: Cytoplasm (By similarity) , Nucleus

Molekulargewicht: 44 kDa

Gen-ID: 5706

UniProt: P62333

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway