AKR1C1 Antikörper

Produktnummer ABIN2855775

Produktdetails anti-AKR1C1 Antikörper

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKR1C1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human

Produktmerkmale: Rabbit polyclonal antibody to DHDH (dihydrodiol dehydrogenase (dimeric))
DHDH antibody [N1C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human DHDH. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: DHDH transfected 293T

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.99 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu AKR1C1

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Andere Bezeichnung: dihydrodiol dehydrogenase (DDH Produkte)

Synonyme: 2-ALPHA-HSD antikoerper, 20-ALPHA-HSD antikoerper, C9 antikoerper, DD1 antikoerper, DD1/DD2 antikoerper, DDH antikoerper, DDH1 antikoerper, H-37 antikoerper, HAKRC antikoerper, HBAB antikoerper, MBAB antikoerper, aldo-keto reductase family 1 member C1 antikoerper, aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) antikoerper, AKR1C1 antikoerper

Hintergrund: This gene encodes an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze the NADP1-linked oxidation of transdihydrodiols of aromatic hydrocarbons to corresponding catechols. This enzyme is a dimeric dihydrodiol dehydrogenase, and it differs from monomeric dihydrodiol dehydrogenases in its high substrate specificity for trans-dihydrodiols of aromatic hydrocarbons in the oxidative direction.

Molekulargewicht: 36 kDa

Gen-ID: 27294

UniProt: Q9UQ10

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process