SLC4A8 Antikörper (N-Term)

Produktnummer ABIN2855611

Produktdetails anti-SLC4A8 Antikörper

Target: SLC4A8 (Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 8 (SLC4A8))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC4A8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus, Ratte (Rattus)

Kreuzreaktivität (Details): Mouse (93 %), Rat (92 %)

Produktmerkmale: Rabbit Polyclonal antibody to SLC4A8 (solute carrier family 4, sodium bicarbonate cotransporter, member 8)
SLC4A8 antibody [N1N2], N-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human SLC4A8. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Kommentare:

Positive Control: IMR32 , U87-MG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.99 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu SLC4A8

Target: SLC4A8 (Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 8 (SLC4A8))

Andere Bezeichnung: SLC4A8 (SLC4A8 Produkte)

Synonyme: SLC4A8 antikoerper, AW493845 antikoerper, C230026C11 antikoerper, NDCBE antikoerper, kNBC-3 antikoerper, NBC3 antikoerper, KNBC3 antikoerper, solute carrier family 4, sodium bicarbonate cotransporter, member 8 S homeolog antikoerper, solute carrier family 4 member 8 antikoerper, solute carrier family 4, sodium bicarbonate cotransporter, member 8 antikoerper, solute carrier family 4 (anion exchanger), member 8 antikoerper, slc4a8.S antikoerper, SLC4A8 antikoerper, slc4a8 antikoerper, Slc4a8 antikoerper

Hintergrund: Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.

Cellular Localization: Membrane, Multi-pass membrane protein

Molekulargewicht: 123 kDa

Gen-ID: 9498