RANBP1 Antikörper

Produktnummer ABIN2855572

Produktdetails anti-RANBP1 Antikörper

Target: RANBP1 (RAN Binding Protein 1 (RANBP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RANBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to Ran BP1 (RAN binding protein 1)
Ran BP1 antibody [N1C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Güteklasse: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the center region of human RanBP1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Mouse brain , HeLaS3 , 293T

Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-RANBP1 Antikörper (ABIN2855572)

Chao, Lai, Lu, Lin, Mai, Huang: "NMDAR signaling facilitates the IPO5-mediated nuclear import of CPEB3." in: Nucleic acids research, Vol. 40, Issue 17, pp. 8484-98, (2012) (PubMed).

Details zu RANBP1

Target: RANBP1 (RAN Binding Protein 1 (RANBP1))

Andere Bezeichnung: RAN binding protein 1 (RANBP1 Produkte)

Synonyme: MGC64314 antikoerper, zeh1094 antikoerper, zgc:85649 antikoerper, hm:zeh1094 antikoerper, wu:fa96a09 antikoerper, wu:fj39g07 antikoerper, HTF9A antikoerper, Htf9a antikoerper, RAN binding protein 1 S homeolog antikoerper, RAN binding protein 1 L homeolog antikoerper, ran binding protein 1 antikoerper, RAN binding protein 1 antikoerper, ran-specific GTPase-activating protein pseudogene antikoerper, ranbp1.S antikoerper, ranbp1.L antikoerper, PVX_090070 antikoerper, GL50803_16969 antikoerper, LOC100343953 antikoerper, ranbp1 antikoerper, RANBP1 antikoerper, Ranbp1 antikoerper

Hintergrund: Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92 % similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.

Molekulargewicht: 23 kDa

Gen-ID: 5902

UniProt: P43487