HLA-DPB1 Antikörper
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- Target Alle HLA-DPB1 Antikörper anzeigen
- HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HLA-DPB1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Human
- Produktmerkmale
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Rabbit Polyclonal antibody to HLA-DPB1 (major histocompatibility complex, class II, DP beta 1)
HLA-DPB1 antibody - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human HLA-DPB1. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product HLA-DPB1 Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Positive Control: Raji
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))
- Andere Bezeichnung
- major histocompatibility complex, class II, DP beta 1 (HLA-DPB1 Produkte)
- Synonyme
- PATR-DPB1 antikoerper, B-LB antikoerper, B-LB2 antikoerper, B-LB21 antikoerper, BLB1 antikoerper, GSP-BLB1 antikoerper, DPB1 antikoerper, HLA-DP antikoerper, HLA-DP1B antikoerper, HLA-DPB antikoerper, major histocompatibility complex, class II, DP beta 1 antikoerper, Major histocompatibility complex class II beta chain BLB1 antikoerper, PATR-DPB1 antikoerper, BLB1 antikoerper, HLA-DPB1 antikoerper
- Hintergrund
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HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
Cellular Localization: Membrane, Single-pass type I membrane protein - Molekulargewicht
- 29 kDa
- Gen-ID
- 3115
- UniProt
- P04440
- Pathways
- T-Zell Rezeptor Signalweg, Cancer Immune Checkpoints
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